Resting-State Functional Brain Networks in Parkinson's Disease
نویسندگان
چکیده
منابع مشابه
Altered Resting State Brain Networks in Parkinson’s Disease
Parkinson's disease (PD) is a neurodegenerative disorder affecting dopaminergic neurons in the substantia nigra leading to dysfunctional cortico-striato-thalamic-cortical loops. In addition to the characteristic motor symptoms, PD patients often show cognitive impairments, affective changes and other non-motor symptoms, suggesting system-wide effects on brain function. Here, we used functional ...
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BACKGROUND Brain network studies using techniques of intrinsic connectivity network based on fMRI time series (TS-ICN) and structural covariance network (SCN) have mapped out functional and structural organization of human brain at respective time scales. However, there lacks a meso-time-scale network to bridge the ICN and SCN and get insights of brain functional organization. METHODOLOGY AND...
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Although alterations of topological organization have previously been reported in the brain functional network of Parkinson's disease (PD) patients, the topological properties of the brain network in early-stage PD patients who received antiparkinson treatment are largely unknown. This study sought to determine the topological characteristics of the large-scale functional network in early-stage...
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Introduction Synchronized low-frequency fluctuations in resting-state fMRI (1) have been used to investigate functional connectivity between brain areas. Recent studies demonstrate that this technique can be utilized in the study of Alzheimers disease (2), antidepressant effects (3), and default mode of brain networks (4). So far, most resting-state fMRI studies have been performed on humans...
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In the absence of any overt task performance, it has been shown that spontaneous, intrinsic brain activity is expressed as systemwide, resting-state networks in the adult brain. However, the route to adult patterns of resting-state activity through neuronal development in the human brain is currently unknown. Therefore, we used functional MRI to map patterns of resting-state activity in infants...
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ژورنال
عنوان ژورنال: CNS Neuroscience & Therapeutics
سال: 2015
ISSN: 1755-5930
DOI: 10.1111/cns.12417